Solutions for the Interaction of CSCs with TAMs

Relying on the technology platform of the tumor microenvironment center, Alfa Cytology provides comprehensive solutions for study the interactions of cancer/tumor stem cells (CSCs) and tumor-associated macrophages (TAMs), helping researchers to successfully achieve their research goals.

Introduction

Compared to general tumor cells, the interaction of cancer/tumor stem cells (CSCs) and tumor-associated macrophages (TAMs) plays a more central role in tumorigenesis, progression, and metastasis formation. CSCs interact with TAMs and mesenchymal cells through multiple levels to form primary TME as well as pre-metastatic sites. Currently, the biological properties of CSCs and the complexity of their interactions with the intricate microenvironment have not been fully elucidated. In particular, the mechanisms that shape the plasticity and malignant phenotype of CSCs during tumor evolution, such as immunogenicity, proliferation rate, differentiation, self-renewal, and migration.

Solutions

Further understanding of how inflammatory signals and immune cells shape the function of CSCs and reprogramming the "dialogue" between TAMs and CSCs can help influence their ability to promote tumor formation, disease progression, and metastasis, and ultimately to eradicate tumors or avoid tumor recurrence. More research will be conducted in this field in the future to utilize this emerging knowledge to provide new ideas and new targets for clinical oncology treatment.

Alfa Cytology has established an innovative tumor microenvironment center technology platform and is developing multiple technologies to study the interactions between cancer stem cells (CSCs) and tumor associated macrophages (TAMs) and how they affect tumorigenesis, progression and metastasis. Based on this technology platform, it is expected to elucidate the mechanisms of their interactions in order to leverage this emerging knowledge to provide new ideas and new targets for clinical tumor therapy.

Key technologies

Alfa Cytology explores the interaction between tumor stem cells (CSCs) and tumor-associated macrophages (TAMs) and the impact of this interaction on other systems by using cell co-culture devices and simulated in vitro models.

Alfa Cytology has a professional tumor animal modeling platform to provide services and solutions on the interaction of tumor stem cells (CSCs) and tumor-associated macrophages (TAMs) and how they affect the processes of tumorigenesis, progression, and metastasis. We can perform individual tests at the most accurate level, and design and complete a range of services as solutions for subject matter projects.

Alfa Cytology is committed to supporting scientists in making breakthrough scientific discoveries and developing new applications to accelerate new drug discovery and scientific diagnosis and treatment. Our high-performance scientific instruments and high-value solutions enable scientists to explore the mysteries of life at the tumor microenvironment level. Please tell us your project requirements, and we will provide you with a full service from solution to report. If you have any questions, please feel free to contact us.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.