Pharmacokinetic Research Services Targeting TME
Relying on the technology platform of the tumor microenvironment center, Alfa Cytology provides a full range of pharmacokinetic research services targeting tumors and microenvironments, which are pushed to the rapid and efficient completion of the project according to the specific requirements of customers.
Introduction
Preclinical pharmacokinetic research is to reveal the dynamic changes of new drugs in animals, and to clarify the dynamic characteristics of drug absorption, distribution, metabolism and excretion (ADME). And according to the mathematical model to provide important kinetic parameters, to preliminarily judge whether it is necessary for further development and research, to participate in the preliminary screening of lead compounds, to provide reference materials for pharmacology, toxicology, pharmacodynamics, clinical trials and clinical rational drug use.
Services
At Alfa Cytology, we have established a mature tumor microenvironment center technology platform, with a group of experienced tumor research experts and mature technologies. We provide high-quality targeted tumor and microenvironment (TME) pharmacokinetic services to our global customers, covering all small molecule/macromolecule (protein and antibody) in vivo pharmacokinetic studies and bioanalysis. The animal species involved are non-human primates, dogs, mice, rats, rabbits, guinea pigs, etc.
Service content
- Mouse / rat / guinea pig / rabbit / dog /minipig / cynomolgus monkey
- Intravenous / subcutaneous / transdermal / intramuscular / intraperitoneal / oral / sublingual / nasal / vitreous
- Cassette dosing/ continuous microblood collection
- Multicycle cross BE/ prescription screening
- Plasma kinetic studies
- Tissue distribution studies
- Excretion studies/ in vivo metabolite identification
- Material balance
- In vivo drug interactions
- Blood-brain barrier permeability
- ADC pharmacokinetic evaluation, etc.
Note: Our services list is constantly being updated and improved, please contact us by email for more up-to-date and relevant information.
Our advantages
- Outstanding professional skills, strong tackling ability
Our mid-level and above management team are all experienced Ph.D., able to provide practical solutions for difficult projects.
- Accumulate a lot of customer cooperation experience
We maintain long-term cooperative relationships with many large pharmaceutical companies and innovative new drug R&D companies around the world, which are trustworthy.
- High service efficiency
The synthesis project is completed quickly, with a high success rate, experienced operators, and cost-effective.
Service process
Alfa Cytology is dedicated to supporting scientists in making groundbreaking scientific discoveries and developing new applications to accelerate new drug discovery and scientific diagnosis and treatment. We have established the tumor microenvironment center technology platform with high performance scientific instruments and high value solutions to ensure high quality services that enable scientists to explore the mysteries of life at the tumor microenvironment level. Please let us know your project requirements and we will provide you with a comprehensive service from solution to report. If you have any questions, please feel free to contact us.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.